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What is the Difference Between Oxycodone and Hydrocodone?

Group of people asking, "What is the difference between Oxycodone and Hydrocodone?"

What is the difference between Oxycodone and Hydrocodone? When it comes to managing pain, these two medications often enter the discussion. While both are opioid analgesics commonly prescribed for moderate to severe pain, they have distinct characteristics and properties that set them apart. Addiction and misuse of these medications are significant concerns due to their potential for abuse and dependence.

Evoke Wellness at Miramar offers opioid addiction treatment programs aimed to address the underlying causes of addiction while helping individuals regain control of their lives and achieve long-term recovery. Call us at 866.931.9312 to learn more.

What Are Oxycodone and Hydrocodone?

Oxycodone is an opioid analgesic medication used for managing moderate to severe pain. Developed in the early 20th century, it aims to offer effective pain relief, especially for chronic pain conditions like osteoarthritis or cancer-related pain. Oxycodone can be found in various forms, including tablets, extended-release tablets, and liquid. Common brand names include OxyContin, Percocet (a combination of Oxycodone and Acetaminophen), and Roxicodone.

Like Oxycodone, Hydrocodone is also an opioid analgesic. It is used to treat moderate to severe pain, as well as to alleviate coughing in certain situations. Hydrocodone was first synthesized in the 1920s and has since become one of the most prescribed pain relief medications in the United States. It is often combined with other pain relievers, such as Acetaminophen, in products like Vicodin and Lortab.

What Is The Difference Between Oxycodone and Hydrocodone?

Oxycodone and Hydrocodone work by binding to specific receptors in the brain and spinal cord known as opioid receptors. These receptors are part of the body’s endogenous painkilling system. By binding to these receptors, these drugs block pain signals from reaching the brain. In turn, this helps reduce the sensation of pain. Additionally, opioids can also affect the brain’s reward system. This leads to feelings of euphoria which can contribute to their potential for abuse. However, what is the difference between Oxycodone and Hydrocodone? Let’s take a closer look.

Breaking Down the Differences

  • Chemical structure – While oxycodone and hydrocodone both belong to the class of medications called opioids, they have slightly different chemical structures. Oxycodone is a semisynthetic opioid derived from thebaine, which is an alkaloid found in the opium poppy. Hydrocodone, on the other hand, is also semisynthetic but is derived from codeine. The differences in their chemical structures can contribute to some differences in how these medications are metabolized in the body and their efficacy in pain relief.
  • Brand names – Oxycodone is sold under several brand names, such as OxyContin, Roxicodone, and Percocet (when combined with acetaminophen). Hydrocodone is also sold under various brand names, including Vicodin, Lortab, and Norco, typically in combination with acetaminophen.
  • Effectiveness – Both oxycodone and hydrocodone are effective at relieving pain, but some studies suggest that oxycodone may be more potent and provide slightly more pain relief than hydrocodone. However, the efficacy can also be subjective and depend on individual patient factors.
  • Side effects – Both medications have similar side effects, including drowsiness, dizziness, nausea, constipation, and the risk of respiratory depression if taken in high doses. However, some individuals may experience different side effects with each medication due to individual differences in metabolism and response.
  • Dosage forms – Oxycodone is available in both immediate-release and extended-release forms, allowing for more flexible dosing options. Hydrocodone is usually found in combination with other medications, most commonly acetaminophen, and typically in immediate-release form.
  • Indications – Oxycodone is typically prescribed for pain relief, while Hydrocodone can also be prescribed as a cough suppressant.

What Is Stronger: Oxycodone or Hydrocodone?

Oxycodone is generally considered to be more potent than hydrocodone. This is due to its pharmacological properties and the way it interacts with the body. Oxycodone is available in both immediate-release and extended-release formulations. It binds directly to opioid receptors in the central nervous system, altering the perception of pain. The binding affinity and activity at the receptor sites contribute to its stronger pain-relieving effects.

Hydrocodone, on the other hand, is typically combined with other non-opioid analgesics like acetaminophen. It is available in immediate-release formulations and is commonly prescribed for moderate pain. While hydrocodone also acts on opioid receptors to provide pain relief, it has a lower potency compared to oxycodone.

Discover Our Opioid Addiction Treatment at Evoke Wellness at Miramar

Evoke Wellness at Miramar offers a comprehensive and personalized approach to opioid addiction treatment. Our experienced team of medical professionals and therapists understands the complexities of opioid addiction and is dedicated to helping individuals overcome their challenges. Call us at 866.931.9312 to learn more.